The Cramer lab focuses on state of the art experimental and theoretical investigations to improve the state of the art of downstream bioprocessing and its successful implementation for the biomanufacturing of biological products. Current multidisciplinary research employs biophysics, multiscale simulations, and chromatography with ligand and protein libraries to design novel and orthogonally selective chromatographic systems. The lab is also investigating integrated and continuous biomanufacturing, expedited process development, gene therapy downstream processing, and hybrid/big data modeling approaches for bioprocessing.
